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The absence of strand‐specific repair for the DNA polymerase pol gene in Deinococcus radiodurans
Author(s) -
Lin ChanShing,
Wang HsiuChin,
Wong Tit.Yee.,
Liu JongKang
Publication year - 1998
Publication title -
iubmb life
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.132
H-Index - 113
eISSN - 1521-6551
pISSN - 1521-6543
DOI - 10.1080/15216549800203052
Subject(s) - deinococcus radiodurans , dna , dna repair , ionizing radiation , pyrimidine dimer , gene , biology , deinococcus , microbiology and biotechnology , polymerase , genetics , chemistry , irradiation , physics , nuclear physics
Deinococcus radiodurans is characterized by its extreme resistance to ionizing radiation. Although Mn+2 was taken up by the cells at a high speed, the absorption of Mn+2 by the cells did not affect their survival rate when irradiated by UV light. However, the Mn‐induced‐cell‐division (Mn‐CD) cells do lose their resistance to UV radiation. This can be explained by the fact that the Mn‐CD cells were less efficient to remove pyrimidine dimers on damaged DNA. We also found that there is no strand‐specific repair of the pol gene in this organism.