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Synthesis and antioxidant activity of water‐soluble chitosan derivatives
Author(s) -
Matsugo Seiichi,
Mizuie Minako,
Matsugo Michiko,
Ohwa Rie,
Kitano Hiromi,
Konishi Tetsuya
Publication year - 1998
Publication title -
iubmb life
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.132
H-Index - 113
eISSN - 1521-6551
pISSN - 1521-6543
DOI - 10.1080/15216549800202002
Subject(s) - chitosan , acylation , tbars , chemistry , antioxidant , thiobarbituric acid , benzoyl peroxide , superoxide , peroxide , organic chemistry , aqueous solution , lipid peroxidation , catalysis , enzyme , polymer , polymerization
We prepared three different water‐soluble chitosan derivatives by the acylation of chitosan with corresponding acid anhydrides. The extent of acylation was determined by using the electric conductivity method. All of the chitosan derivatives were soluble enough to examine the respective mltioxidant activity in aqueous media. The chitosan derivatives inhibited thiobarbituric acid reactive substrate (TBARS) formation in t‐butyl hydroperoxide and benzoyl peroxide induced lipid peroxidations. However, they did not show any scavenging activity toward superoxide.