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Cloning and sequencing of the secY gene homolog from Mycobacterium bovis BCG
Author(s) -
Kim Jin Koo,
Kim Jeong Hyun,
Kim Jae Wha,
Lee Younghee,
Lim JongSeok,
Lee Hee Gu,
Choe In Seong,
Chung Tai Wha,
Park SueNie,
Ahn Jong Seog,
Choe YongKyung,
Kim Sang Jae,
Bai Gill Han,
Cho SangHyun,
Kang Sang Won,
Kim Yu Sam
Publication year - 1997
Publication title -
iubmb life
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.132
H-Index - 113
eISSN - 1521-6551
pISSN - 1521-6543
DOI - 10.1080/15216549700204181
Subject(s) - open reading frame , gene , biology , homology (biology) , genetics , mycobacterium bovis , nucleic acid sequence , cloning (programming) , peptide sequence , sequence analysis , amino acid , microbiology and biotechnology , mycobacterium tuberculosis , medicine , tuberculosis , pathology , computer science , programming language
The complete nucleotide sequence of a 1,513 bp fragment of Mycobacterium bovis BCG containing the secY gene homolog and partial adk gene that encodes an adenylate kinase has been determined. The secY gene of BCG has an open reading frame of 441 amino acids with homology to the SecY protein family. Comparative analyses of the deduced amino acid sequence of additional partial ORF revealed strong similarity to the known adenylate kinases.