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Transport of glutathione S‐conjugates in Escherichia coli
Author(s) -
Kałuzna Agnieszka,
Bartosz Grzegorz
Publication year - 1997
Publication title -
iubmb life
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.132
H-Index - 113
eISSN - 1521-6551
pISSN - 1521-6543
DOI - 10.1080/15216549700203931
Subject(s) - glutathione , escherichia coli , conjugate , vanadate , biochemistry , chemistry , enzyme , gene , mathematical analysis , mathematics
There are no reports concerning glutathione‐S‐conjugates transport in prokaryotic cells, although many studies have been performed in eukaryotic systems. This study demonstrates that glutathione S‐conjugates (2,4‐dinitrophenyl‐S‐glutathione and bimane‐S‐glutathione) are transported also out of Escherichia coli K12 cells. This transport is inhibited by vanadate, fluoride and other inhibitors of glutathione S‐conjugate transport in mammalian cells suggesting a similarity of this process to that known in eukaryotes.