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2′3′‐CNPase and actin distribution in oligodendrocytes, relative to their mRNAs
Author(s) -
McEwan Neil R.
Publication year - 1996
Publication title -
iubmb life
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.132
H-Index - 113
eISSN - 1521-6551
pISSN - 1521-6543
DOI - 10.1080/15216549600201603
Subject(s) - immunocytochemistry , oligodendrocyte , in situ hybridization , microbiology and biotechnology , biology , messenger rna , cell , myelin , gene , central nervous system , neuroscience , genetics , endocrinology
By using oligodendrocyte cells, which have a very highly defined cell morphology, it is demonstrated that, in general, proteins are found slightly more distal, relative to the cell body, than their mRNA counterparts, but that there is a general trend for proteins and the messages which encode them to be found in similar regions within the cell. This has been demonstrated by use of in situ hybridization and immunocytochemistry together on single cells.