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Neurogenesis: Is the Adult Stem Cell Young or Old?
Author(s) -
Ricard Jerome,
Liebl Daniel J.
Publication year - 2004
Publication title -
iubmb life
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.132
H-Index - 113
eISSN - 1521-6551
pISSN - 1521-6543
DOI - 10.1080/15216540310001659452
Subject(s) - neurogenesis , stem cell , neuroscience , embryonic stem cell , neural stem cell , biology , adult stem cell , stem cell biology , stem cell therapy , spinal cord injury , embryo , spinal cord , microbiology and biotechnology , embryogenesis , genetics , reproductive technology , gene
Stem cell biology is one of the most exciting, controversial, and debated fields in science today. It has been suggested that neuronal replacement therapy using stem cell transplants may be one possible answer to a host of neuropathological disorders including spinal cord injury, stroke, and neurodegenerative diseases. Important sources for stem cells include the developing embryo and adult central nervous system, but will these populations of cells exhibit similar behavior and responses to stimuli? This review will discuss some important similarities and differences between the embryonic and adult stem cell, as well as the basis for developing therapeutic approaches for stem cell replacement.IUBMB Life, 56: 1‐6, 2004