Competitive, Reversible, Physiological? Inhibition of Mitochondrial Cytochrome Oxidase by Nitric Oxide | Zendy

Cooper Chris | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Competitive, Reversible, Physiological? Inhibition of Mitochondrial Cytochrome Oxidase by Nitric Oxide

Author(s) -

Cooper Chris

Publication year - 2003

Publication title -

iubmb life

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.132

H-Index - 113

eISSN - 1521-6551

pISSN - 1521-6543

DOI - 10.1080/15216540310001628663

Subject(s) - cytochrome c oxidase , nitric oxide , oxygen , chemistry , mitochondrion , cytochrome , oxidase test , cytochrome c , enzyme , electron transport complex iv , biochemistry , organic chemistry

In the mid 1990s a number of research groups recognized that mitochondrial oxygen consumption could be reversibly inhibited by nitric oxide at the level of the enzyme cytochrome c oxidase. The inhibition was apparently competitive with respect to the oxygen concentration. This review critically assesses the present state of knowledge as regards the hypothesis that nitric oxide is a competitive, reversible, physiological inhibitor of cytochrome oxidase. IUBMB Life, 55: 591‐597, 2003

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research