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Kaposi's Sarcoma Biology
Author(s) -
Boshoff Chris
Publication year - 2002
Publication title -
iubmb life
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.132
H-Index - 113
eISSN - 1521-6551
pISSN - 1521-6543
DOI - 10.1080/15216540212645
Subject(s) - sarcoma , malignancy , virology , carcinogenesis , cancer , oncovirus , virus , human immunodeficiency virus (hiv) , biology , immunity , immunology , medicine , immune system , pathology , genetics
Abstract Cancer remains a major burden for HIV‐infected individuals. The majority of cancers associated with HIV infection are driven by oncogenic viruses like Epstein‐Barr virus, Kaposi's sarcoma‐associated herpesvirus and human papillomavirus. Kaposi's sarcoma is a tumour of endothelium and is the most common malignancy in HIV infected individuals. AIDS‐related cancers are providing critical insight into cancer immunity and viral oncogenesis.