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From Cytosol to Organelles: 14‐3‐3 Proteins as Multifunctional Regulators of Plant Cell
Author(s) -
Aducci Patrizia,
Camoni Lorenzo,
Marra Mauro,
Visconti Sabina
Publication year - 2002
Publication title -
iubmb life
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.132
H-Index - 113
eISSN - 1521-6551
pISSN - 1521-6543
DOI - 10.1080/15216540210813
Subject(s) - cytosol , organelle , microbiology and biotechnology , biology , function (biology) , mitochondrion , chloroplast , cellular compartment , transcription factor , cellular metabolism , phosphorylation , gene , cell , biochemistry , metabolism , enzyme
14‐3‐3 proteins are a class of highly conserved proteins widespread in eukaryotes. They regulate several cellular processes through phosphorylation‐dependent interaction with their targets. Since their discovery in plants, a number of peculiar functions have been ascertained, such as regulation of primary metabolism, ion transport, cellular trafficking, chloroplast and mitochondrial enzyme activities and gene transcription. The still increasing body of evidence suggests that 14‐3‐3s may function as versatile proteins able to move from cytosol to different cellular organelles. This review will focus on the broad range of regulatory tasks carried out by 14‐3‐3s in the different compartments.