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The Peroxisome in Oxidative Stress
Author(s) -
Dansen Tobias B.,
Wirtz Karel W. A.
Publication year - 2001
Publication title -
iubmb life
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.132
H-Index - 113
eISSN - 1521-6551
pISSN - 1521-6543
DOI - 10.1080/152165401753311762
Subject(s) - peroxisome , oxidative stress , microbiology and biotechnology , radical , reactive oxygen species , oxidative phosphorylation , chemistry , cell , homeostasis , oxygen , carcinogenesis , biochemistry , biology , receptor , gene , organic chemistry
Peroxisomes are one of the main sites in the cell where oxygen free radicals are both generated and scavenged. The balance between these two processes is believed to be of great importance for proper functioning of cells and has been implicated in aging and carcinogenesis. We will give an overview of the peroxisomal processes involved in the oxygen radical homeostasis and its implications for the cell.