Premium
Kaposi's Sarcoma‐Associated Herpesvirus: From Cell Biology to Pathogenesis
Author(s) -
Sharp Tyson V.,
Boshoff Chris
Publication year - 2000
Publication title -
iubmb life
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.132
H-Index - 113
eISSN - 1521-6551
pISSN - 1521-6543
DOI - 10.1080/15216540050022395
Subject(s) - pathogenesis , virology , human herpesvirus , sarcoma , biology , medicine , immunology , cancer research , virus , pathology
Kaposi's sarcoma‐associated herpesvirus (KSHV or HHV‐8) is linked to the etiopathogenesis of Kaposi's sarcoma, a plasmablastic variant of Castleman's disease and primary effusion lymphoma. KSHV is related to a number of non‐human primate viruses. Only a limited number of KSHV proteins are expressed in tumor cells. Here we discuss the putative role of these proteins in KSHV pathogenesis.