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Central pontine myelinolysis in a normonatraemic alcoholic patient
Author(s) -
MUNDLE GÖTZ,
FRIESE SIGRID,
KÖHNKE MICHAEL D.
Publication year - 1999
Publication title -
addiction biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.445
H-Index - 78
eISSN - 1369-1600
pISSN - 1355-6215
DOI - 10.1080/13556219971579
Subject(s) - central pontine myelinolysis , etiology , electrolyte disorder , magnetic resonance imaging , medicine , derangement , malnutrition , proton magnetic resonance , hyponatremia , pediatrics , radiology , nuclear magnetic resonance , mathematics , combinatorics , physics
Central pontine myelinolysis (CPM) is a rare disease which has been associated with hyponatraemia and its rapid correction. We describe a malnourished 32‐year‐old alcohol‐dependent woman suffering from an infection who had developed CPM without any known prior derangement in serum electrolytes or its iatrogenic correction. Computerized tomography (CT) and magnetic resonance imaging (MRI) played an important role in the diagnosis. Even when an electrolyte derangement is absent, alcoholism, malnourishment and infection should be considered as important possible aetiological factors of CPM.