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Liver disease due to illicit substance use
Author(s) -
RIORDAN STEPHEN M.,
WILLIAMS ROGER
Publication year - 1998
Publication title -
addiction biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.445
H-Index - 78
eISSN - 1369-1600
pISSN - 1355-6215
DOI - 10.1080/13556219872335
Subject(s) - phencyclidine , ecstasy , hallucinogen , heroin , medicine , illicit drug , liver damage , liver disease , lysergic acid diethylamide , liver injury , pharmacology , psychiatry , drug , nmda receptor , receptor , serotonin
While the adverse neurological, cardiovascular, renal, haematologic and musculoskeletal consequences of the use of various illicit substances are widely appreciated, less attention has been directed to possible hepatotoxic effects. This is an important issue in view of increasing evidence in both experimental animals and humans that the use of some illicit substances may be associated with substantial liver damage, leading on occasion to acute liver failure. This manuscript reviews the effects on the liver of some of the most commonly used illicit substances, including ecstasy (3,4‐methylenedioxymethamphetamine), other amphetamines, cocaine, heroin, angel dust (phencyclidine), lysergic acid diethylamide and marijuana. Additional causes of liver damage in those using illicit substances are discussed.