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Enhanced prolactin levels in opium smokers
Author(s) -
MoshtaghiKashanian GhollamReza,
Esmaeeli Farzaneh,
Dabiri Shahriar
Publication year - 2005
Publication title -
addiction biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.445
H-Index - 78
eISSN - 1369-1600
pISSN - 1355-6215
DOI - 10.1080/13556210500351263
Subject(s) - opium , prolactin , codeine , nicotine , morphine , medicine , testosterone (patch) , pleasure , pharmacology , endocrinology , psychology , hormone , neuroscience , geography , archaeology
In Iran, opium is smoked for pleasure or as a medication by some people. It is a complex mixture of 40 different alkaloids, including morphine and codeine along with many impurities. Although it is well established that opioids or tobacco affect many physiological functions in humans, to our knowledge there has been no specific study looking at these effects in opium smokers. To assess that, we investigated the circulating levels of prolactin, TSH, LH, FSH and testosterone in male opium smokers who also smoke cigarettes (n =23, aged 28.4?4.1 years), and comparing this with the corresponding values for nicotine abusers (n =12, 15–25 cigarettes/day) or a healthy control group (n =20) of the same age. Our results showed that 86.96% of the opium‐dependent and 41.67 % of the nicotine‐dependent group displayed high prolactin values (p)