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Outcomes of Naltrexone Maintenance Following Ultra Rapid Opiate Detoxification Versus Intensive Inpatient Detoxification
Author(s) -
Rabinowitz Jonathan,
Cohen Hagit,
Atias Shmuel
Publication year - 2002
Publication title -
the american journal on addictions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.997
H-Index - 76
eISSN - 1521-0391
pISSN - 1055-0496
DOI - 10.1080/10550490252801639
Subject(s) - detoxification (alternative medicine) , naltrexone , opiate , clonidine , medicine , psychiatry , anesthesia , opioid , alternative medicine , receptor , pathology
Relapse rates of 30 opiate‐addicted social service clients who were given a 9‐month course of naltrexone after being rapidly detoxified using naltrexone + clonidine under anesthesia were compared to 33 similar clients detoxified in a 30‐day intensive inpatient detoxification but not given naltrexone. Both groups had the same counseling aftercare. Telephone follow‐up of 26 of the intensive inpatient detoxification clients and 24 of the rapidly detoxified clients found no significant differences (p = .62) in relapse rates, with 34% of respondents returning to regular opiate use 13.4 (± 3.8) months after detoxification. Naltrexone maintenance and counseling following rapid detoxification may be as effective as intensive inpatient detoxification and counseling.

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