Premium
The use of carbamazepine in chlormethiazole‐modified withdrawal from alcohol
Author(s) -
Stanhope John M.,
Curry Kenneth H.
Publication year - 1989
Publication title -
australian drug and alcohol review
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.018
H-Index - 74
eISSN - 1465-3362
pISSN - 0819-5331
DOI - 10.1080/09595238980000021
Subject(s) - carbamazepine , placebo , anesthesia , alcohol , medicine , psychology , incidence (geometry) , placebo group , epilepsy , psychiatry , chemistry , biochemistry , physics , alternative medicine , pathology , optics
Summary: The effect on seizure frequency and other withdrawal symptoms of the addition of carbamazepine or placebo was compared in 304 patients being managed during alcohol withdrawal. Patients were studied for a minimum of four days, unless terminated earlier by self‐discharge. The incidence of seizures was 2 % in both test and placebo groups. The addition of carbamazepine was not found useful in the management of alcohol withdrawal, but the low frequency of fits may have masked an effect. Such a low frequency had not been anticipated when the study was planned.