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Sensory evoked potentials in infants with Down syndrome
Author(s) -
CHEN YUNGJUNG,
FANG PENGCHENG
Publication year - 2005
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1080/08035250500252609
Subject(s) - medicine , audiology , somatosensory evoked potential , sensory system , brainstem , brainstem auditory evoked potential , evoked potential , latency (audio) , sensory processing , somatosensory system , peripheral , visual evoked potentials , auditory pathways , anesthesia , neuroscience , psychology , psychiatry , electrical engineering , engineering
Aim : To investigate the sensory functions of the peripheral to central pathways in infants with Down syndrome (DS) by sensory evoked potentials. Methods: Fifty‐five infants, 30 DS infants and 25 controls, were examined by multimodal evoked potentials, including brainstem auditory evoked potentials (BAEP), visual evoked potentials (VEP) and short‐latency somatosensory evoked potentials (SSEP). Results: No obvious difference was found in the peak latencies between the two groups for BAEP. Nine children with DS showed abnormal BAEP; six had hearing loss and three had prolonged wave I latencies. For VEP, the peak latencies of P 2 and N 2 were significantly longer and the amplitudes were smaller in the DS group than in the control group. Of the 30 infants with DS, five had significantly prolonged P 2 latencies and two had lower amplitudes. In SSEP, the mean latencies of N 20 and the interpeak latencies of N 13 ‐N 20 of the infants with DS showed apparent prolongation compared to the controls. Seven of 30 (23.3%) DS patients had prolonged N 20 latencies. Conclusion: Our results indicate that various sensory deficits occur in patients with DS during the first year of life.