Role of Epigenetics in Mental Disorders | Zendy

Selma Stuffrein-Roberts | Zendy; Peter R. Joyce | Zendy; Martin A. Kennedy | Zendy

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Role of Epigenetics in Mental Disorders

Author(s) -

Selma Stuffrein-Roberts,

Peter R. Joyce,

Martin A. Kennedy

Publication year - 2008

Publication title -

australian and new zealand journal of psychiatry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.66

H-Index - 116

eISSN - 1440-1614

pISSN - 0004-8674

DOI - 10.1080/00048670701787495

Subject(s) - epigenetics , epigenesis , psychology , medicine , psychiatry , biology , dna methylation , genetics , gene expression , gene

The purpose of this paper was to selectively review the literature on the role of epigenetics in mental illnesses. Aberrant epigenetic regulation has been clearly implicated in the aetiology of some human illnesses. In recent years a growing body of evidence has highlighted the possibility that epigenetics may also play a key role in the origins and expression of mental disorders. Epigenetic phenomena may help explain some of the complexity of mental illnesses and provide a basis for discovering novel pharmacological targets to treat these disorders.

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