Open AccessCryopreserved blastocysts have a lower implantation but an equal live birth rate as compared to fresh blastocysts of the same quality – a case–control study
Author(s) -
SHEBL OMAR,
EBNER THOMAS,
SOMMERGRUBER MICHAEL,
SIR ANDREAS,
TEWS GERNOT
Publication year - 2009
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1080/00016340903093575
Subject(s) - cryopreservation , live birth , medicine , embryo , pregnancy rate , embryo transfer , embryo cryopreservation , pregnancy , embryo quality , andrology , assisted reproductive technology , gynecology , obstetrics , in vitro fertilisation , biology , infertility , genetics , microbiology and biotechnology
The purpose of this case–control study was to compare implantation, pregnancy, and live birth rate of cryopreserved embryos with that of fresh embryos. A total of 1,488 assisted reproductive technology (ART) trials including 188 cryopreserved embryo replacement trials were reviewed. After proofing the exclusion criteria, 112 patients undergoing a cryopreserved embryo replacement (study group) were matched with 112 patients undergoing a fresh embryo transfer (control group). Matching was done for age of patients, number, and quality of embryos (Day 5 embryos). Data concerning maternal characteristics, survival rate of warming procedure, implantation, pregnancy, ongoing pregnancy, and live birth rates were collected. A lower implantation rate was found for cryopreserved embryo replacement compared to transferring fresh embryos. Live birth rate was found to be equal in both groups.