
Diversity among Purkinje cells in the monkey cerebellum.
Author(s) -
Ver M. Ingram,
Marilee P. Ogren,
Clare L. Chatot,
Jamie M. Gossels,
Barbara Blanchard Owens
Publication year - 1985
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.82.20.7131
Subject(s) - cerebellum , forebrain , spinal cord , biology , neuroscience , cerebellar cortex , antigen , cerebral cortex , cortex (anatomy) , anatomy , somatosensory system , central nervous system , immunology
A monoclonal antibody (B1) produced against rat embryonic forebrain membranes shows specific and striking immunohistochemical staining of Purkinje cells in the monkey cerebellum in a pattern of broad parasagittal alternating bands of cells either possessing or lacking the B1 antigen. In addition, the neurons of the deep cerebellar nuclei and some neurons of the motor cortex and of the spinal cord also contain the B1 antigen. Neurons with the B1 antigen were also seen in the somatosensory cortex, the vestibular and cochlear nuclei, and the retina.