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Ribosomal RNA Homologies among Distantly Related Organisms
Author(s) -
Arnold J. Bendich,
Brian J. McCarthy
Publication year - 1970
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.65.2.349
Subject(s) - ribosomal rna , biology , phylogenetic tree , 5.8s ribosomal rna , genetics , 18s ribosomal rna , 28s ribosomal rna , rna , internal transcribed spacer , phylogenetics , ribosomal dna , 23s ribosomal rna , 5s ribosomal rna , dna , ribosome , gene
The similarity in base sequences of ribosomal RNA (rRNA) in widely divergent organisms was compared. Hybrids were prepared betweenEscherichia coli and pea rRNA on the one hand and the DNA of several organisms on the other. The varying thermal stabilities of these hybrids were taken as evidence for a hierarchy of rRNA relatedness among some higher plants, and for phylogenetic relationships among some species of bacteria, protozoa, fungi, plants, and animals. The large rRNA molecule appears to have evolved faster than the small rRNA molecule.

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