Open AccessThe Gasdermin D N-terminal fragment acts as a negative feedback system to inhibit inflammasome-mediated activation of Caspase-1/11
Author(s) -
Yunzhang Hu,
Yanni Jiang,
Sheng Li,
Xiang Ma,
Min Chen,
Rui Yang,
Shuang Wen,
Paul N. Moynagh,
Bingwei Wang,
Gang Hu,
Shuo Yang
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2210809119
Subject(s) - inflammasome , pyroptosis , microbiology and biotechnology , caspase 1 , cleavage (geology) , regulator , inflammation , chemistry , caspase , peptide , biology , programmed cell death , apoptosis , biochemistry , immunology , paleontology , fracture (geology) , gene