Open AccessOmics analyses of a somatic Trp53 R245W/+ breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling
Author(s) -
Xiaomei Yu,
Yun Zhang,
Shunbin Xiong,
Joy M. McDaniel,
Chang Sun,
Gilda P. Chau,
Jovanka Gencel-Augusto,
Dhruv Chachad,
Rhian Morrissey,
Xiayu Rao,
Jing Wang,
Guillermina Lozano
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2210618119
Subject(s) - pi3k/akt/mtor pathway , pten , protein kinase b , breast cancer , cancer research , cancer , rptor , biology , phosphorylation , signal transduction , medicine , genetics