Open AccessCGG repeat expansion in NOTCH2NLC causes mitochondrial dysfunction and progressive neurodegeneration in Drosophila model
Author(s) -
Jiaxi Yu,
Tongling Liufu,
Yilei Zheng,
Jin Xu,
Lingchao Meng,
Wei Zhang,
Yun Yuan,
Daojun Hong,
Nicolas CharletBerguerand,
Zhaoxia Wang,
Jianwen Deng
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2208649119
Subject(s) - neurodegeneration , biology , mitochondrion , transgene , microbiology and biotechnology , genetically modified mouse , trinucleotide repeat expansion , immunoelectron microscopy , pathology , gene , genetics , medicine , disease , allele , antibody