PTX3 structure determination using a hybrid cryoelectron microscopy and AlphaFold approach offers insights into ligand binding and complement activation
Author(s) -
Dylan P. Noone,
Douwe J. Dijkstra,
Teun T. van der Klugt,
Peter A. van Veelen,
Arnoud H. de Ru,
Paul J. Hensbergen,
Leendert A. Trouw,
Thomas H. Sharp
Publication year - 2022
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2208144119
Subject(s) - ptx3 , computational biology , protein quaternary structure , innate immune system , biology , chemistry , biophysics , inflammation , biochemistry , immunology , receptor , protein subunit , gene
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