Open AccessOrexin 2 receptor–selective agonist danavorexton improves narcolepsy phenotype in a mouse model and in human patients
Author(s) -
Rebecca Evans,
Haruhide Kimura,
Robert Alexander,
Ceri H. Davies,
Hélène M. Faessel,
Deborah S. Hartman,
Takashi Ishikawa,
Emiliangelo Ratti,
Kohei Shimizu,
Motohisa Suzuki,
Shinichiro Tanaka,
Hiroshi Yukitake,
Yves Dauvilliers,
Emmanuel Mignot
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2207531119
Subject(s) - narcolepsy , orexin , wakefulness , agonist , endocrinology , medicine , cataplexy , orexin receptor , sleep (system call) , orexin a , receptor , chemistry , neuroscience , biology , neuropeptide , neurology , electroencephalography , computer science , operating system