Orexin 2 receptor–selective agonist danavorexton improves narcolepsy phenotype in a mouse model and in human patients
Author(s) -
Rebecca Evans,
Haruhide Kimura,
Robert Alexander,
Ceri H. Davies,
Hélène M. Faessel,
Deborah Hartman,
Takashi Ishikawa,
Emiliangelo Ratti,
Kohei Shimizu,
Motohisa Suzuki,
Shinichiro Tanaka,
Hiroshi Yukitake,
Yves Dauvilliers,
Emmanuel Mignot
Publication year - 2022
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2207531119
Subject(s) - narcolepsy , orexin , wakefulness , agonist , cataplexy , endocrinology , medicine , sleep (system call) , orexin receptor , receptor , neuroscience , biology , pharmacology , neuropeptide , modafinil , electroencephalography , computer science , operating system
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom