Open AccessDirected evolution identifies high-affinity cystine-knot peptide agonists and antagonists of Wnt/β-catenin signaling
Author(s) -
Simon Hansen,
Yingnan Zhang,
SunHee Hwang,
Ahmad Nabhan,
Wanqing Li,
Jakob Fuhrmann,
Yvonne T. Kschonsak,
Lijuan Zhou,
Aaron H. Nile,
Xinxin Gao,
Robert Piskol,
Felipe de Sousa e Melo,
Frédéric J. de Sauvage,
Rami N. Hannoush
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2207327119
Subject(s) - wnt signaling pathway , microbiology and biotechnology , biology , agonist , signal transduction , receptor , g protein coupled receptor , chemistry , biochemistry