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Brain endothelial STING1 activation by Plasmodium -sequestered heme promotes cerebral malaria via type I IFN response
Author(s) -
Teresa F. Pais,
Hajrabibi Ali,
Joana Moreira da Silva,
Nádia Duarte,
Rita Neres,
Chintan Chhatbar,
Rita C. Acúrcio,
Rita C. Guedes,
Maria Carolina Strano Moraes,
Bruno CostaSilva,
Ulrich Kalinke,
Carlos PenhaGonçalves
Publication year - 2022
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2206327119
Subject(s) - plasmodium berghei , cerebral malaria , heme , biology , microbiology and biotechnology , blood–brain barrier , hemozoin , inflammation , endothelium , interferon , neuroinflammation , immunology , microglia , cxcl10 , chemokine , interferon gamma , immune system , plasmodium falciparum , central nervous system , neuroscience , biochemistry , malaria , enzyme , endocrinology

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