Open AccessMetabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer’s disease
Author(s) -
Abbas Dehghan,
Rui Pinto,
Íbrahím Karaman,
Jian Huang,
Brenan R. Durainayagam,
Mohsen Ghanbari,
Areesha Nazeer,
Qi Zhong,
Sonia Liggi,
Luke Whiley,
Rima Mustafa,
Miia Kivipelto,
Alina Solomon,
Tiia Ngandu,
Takahisa Kanekiyo,
Tomonori Aikawa,
Carola I. Radulescu,
Samuel J. Barnes,
Gonçalo Graça,
Elena Chekmeneva,
Stéphane Camuzeaux,
Matthew R. Lewis,
Manuja Kaluarachchi,
M. Arfan Ikram,
Elaine Holmes,
Ioanna Tzoulaki,
Paul M. Matthews,
Julian L. Griffin,
Paul Elliott
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2206083119
Subject(s) - sphingolipid , metabolome , ceramide , metabolomics , single nucleotide polymorphism , biology , genetic association , sphingosine , genome wide association study , alzheimer's disease , genetics , biochemistry , gene , disease , medicine , bioinformatics , genotype , apoptosis , receptor