Open AccessCorrelation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes
Author(s) -
Halina Mikolajek,
Miriam Weckener,
Z. Faidon Brotzakis,
Jiandong Huo,
Evmorfia V Dalietou,
Audrey Le Bas,
Pietro Sormanni,
Peter Harrison,
Philip N. Ward,
Steven Truong,
L. Moynié,
Daniel K. Clare,
Maud Dumoux,
Joshua Dormon,
Chelsea Norman,
Naveed Hussain,
Vinod K. Vogirala,
Raymond J. Owens,
Michele Vendruscolo,
James H. Naismith
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2205412119
Subject(s) - biophysics , conformational entropy , chemistry , coronavirus , conformational change , plasma protein binding , protein structure , binding domain , entropy (arrow of time) , binding affinities , computational biology , binding site , biology , biochemistry , receptor , covid-19 , molecule , organic chemistry , medicine , physics , disease , pathology , quantum mechanics , infectious disease (medical specialty)