Open AccessChemical interference with DSIF complex formation lowers synthesis of mutant huntingtin gene products and curtails mutant phenotypes
Author(s) -
Ning Deng,
Yue Wu,
Feng Yin,
WenYuan Hsieh,
JenShin Song,
Yu-Shiuan Lin,
Ya-Hsien Tseng,
Wan-Jhu Liao,
Yifan Chu,
Yu Cheng Liu,
En-Cheng Chang,
Chia-Rung Liu,
Sheh Yi Sheu,
M. Su,
HungChih Kuo,
Stanley N. Cohen,
Tso-Hsin Cheng
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2204779119
Subject(s) - huntingtin , mutant , biology , microbiology and biotechnology , gene , gene expression , drosophila melanogaster , phenotype , rna interference , allele , genetics , rna