Chemical interference with DSIF complex formation lowers synthesis of mutant huntingtin gene products and curtails mutant phenotypes
Author(s) -
Ning Deng,
Yunyun Wu,
Yanan Feng,
Wen-Chieh Hsieh,
JenShin Song,
Yu-Shiuan Lin,
YaHsien Tseng,
Wan-Jhu Liao,
Yifan Chu,
YuCheng Liu,
En-Cheng Chang,
Chia-Rung Liu,
ShehYi Sheu,
M. Su,
HungChih Kuo,
Stanley N. Cohen,
TzuHao Cheng
Publication year - 2022
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2204779119
Subject(s) - huntingtin , mutant , biology , microbiology and biotechnology , gene , gene expression , drosophila melanogaster , phenotype , rna interference , allele , genetics , rna
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