Open AccessHeterozygous LRP1 deficiency causes developmental dysplasia of the hip by impairing triradiate chondrocytes differentiation due to inhibition of autophagy
Author(s) -
Wenjin Yan,
Liming Zheng,
Xingquan Xu,
Hao Zheng,
Hongjie Zhang,
Jun Lü,
Ziying Sun,
Jin Dai,
Dongquan Shi,
Baosheng Guo,
Qing Jiang
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2203557119
Subject(s) - lrp1 , biology , chondrocyte , chondrogenesis , phenotype , missense mutation , compound heterozygosity , cancer research , genetics , endocrinology , gene , ldl receptor , cell , lipoprotein , in vitro , cholesterol