Open AccessCryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes
Author(s) -
You Yu,
Shibai Li,
Zheng Ser,
Huihui Kuang,
Thane Than,
Danying Guan,
Xiaolan Zhao,
Dinshaw J. Patel
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2202799119
Subject(s) - dna clamp , dna , replication protein a , chromatin , dna replication , protein subunit , hmg box , biology , dna repair , biophysics , cohesin , microbiology and biotechnology , biochemistry , dna binding protein , transcription factor , reverse transcriptase , rna , gene