Open AccessA set point in the selection of the αβTCR T cell repertoire imposed by pre-TCR signaling strength
Author(s) -
Elena R. Bovolenta,
Eva M. GarcíaCuesta,
Lydia Horndler,
Julia Ponomarenko,
Wolfgang W. A. Schamel,
Mario Mellado,
Mario Castro,
David Abia,
Hisse M. van Santen
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2201907119
Subject(s) - t cell receptor , repertoire , biology , negative selection , allelic exclusion , signal transduction , microbiology and biotechnology , cd3 , selection (genetic algorithm) , t cell , antigen , genetics , immune system , genome , gene , cd8 , computer science , physics , acoustics , artificial intelligence