
Agonist concentration–dependent changes in FPR1 conformation lead to biased signaling for selective activation of phagocyte functions
Author(s) -
Junlin Wang,
Richard D. Ye
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2201249119
Subject(s) - chemotaxis , n formylmethionine leucyl phenylalanine , phagocyte , superoxide , microbiology and biotechnology , degranulation , agonist , intracellular , biology , signal transduction , biochemistry , chemistry , receptor , biophysics , phagocytosis , enzyme