Open AccessProximity interactome analysis of Lassa polymerase reveals eRF3a/GSPT1 as a druggable target for host-directed antivirals
Author(s) -
Jingru Fang,
Colette Pietzsch,
Haydar Witwit,
George Tsaprailis,
Gogce Crynen,
Kelvin Frank Cho,
Alice Y. Ting,
Alexander Bukreyev,
Erica Ollmann Saphire,
Juan Carlos de la Torre
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2201208119
Subject(s) - lassa virus , biology , polymerase , interactome , rna polymerase , virology , rna dependent rna polymerase , druggability , proteome , rna polymerase ii , rna , computational biology , virus , genetics , gene expression , dna , gene , promoter