Proximity interactome analysis of Lassa polymerase reveals eRF3a/GSPT1 as a druggable target for host-directed antivirals
Author(s) -
Jingru Fang,
Colette Pietzsch,
Haydar Witwit,
George Tsaprailis,
Gogce Crynen,
Kelvin F. Cho,
Alice Y. Ting,
Alexander Bukreyev,
Erica Ollmann Saphire,
Juan Carlos de la Torre
Publication year - 2022
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2201208119
Subject(s) - biology , lassa virus , interactome , polymerase , rna polymerase , virology , rna dependent rna polymerase , proteome , druggability , rna polymerase ii , rna , computational biology , virus , genetics , dna , gene expression , gene , promoter
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