
Structural basis of peptidomimetic agonism revealed by small-molecule GLP-1R agonists Boc5 and WB4-24
Author(s) -
Zhaotong Cong,
Qingtong Zhou,
Yang Li,
Li-Nan Chen,
Zi-Chen Zhang,
Anyi Liang,
Qing Liu,
Xiaoyan Wu,
Antao Dai,
Tian Xia,
Wei Wu,
Yan Zhang,
Dehua Yang,
Mingwei Wang
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2200155119
Subject(s) - peptidomimetic , chemistry , agonist , pharmacology , g protein coupled receptor , agonism , functional selectivity , in vivo , drug discovery , receptor , stereochemistry , peptide , biochemistry , medicine , biology , microbiology and biotechnology , politics , political science , law