Open AccessDiscovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections
Author(s) -
Ram K. Modukuri,
Zhifeng Yu,
Zhi Tan,
Hai Minh Ta,
Melek N. Ucisik,
Zhuang Jin,
Justin L. Anglin,
Kiran Sharma,
Pranavanand Nyshadham,
Feng Li,
Kevin Riehle,
John C. Faver,
Kevin Duong,
Sureshbabu Nagarajan,
Nicholas Simmons,
Stephen Palmer,
Mingxing Teng,
Damian W. Young,
Joanna Yi,
Choel Kim,
Martin M. Matzuk
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2122506119
Subject(s) - bromodomain , brd4 , phenocopy , small molecule , drug discovery , chemistry , computational biology , pharmacology , biology , dna , biochemistry , gene , histone , phenotype