
Computationally guided conversion of the specificity of E-selectin to mimic that of Siglec-8
Author(s) -
Xiaocong Wang,
Melinda S. Hanes,
Richard D. Cummings,
Robert J. Woods
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2117743119
Subject(s) - glycan , chemistry , ligand (biochemistry) , oligosaccharide , sulfation , glycobiology , biochemistry , siglec , selectin , lectin , recombinant dna , sialyl lewis x , glycoproteomics , glycoprotein , endogeny , receptor , gene , organic chemistry , adhesion