Open AccessMyeloid caspase-8 restricts RIPK3-dependent proinflammatory IL-1β production and CD4 T cell activation in autoimmune demyelination
Author(s) -
Sun-Ja Kim,
Hsueh Chung Lu,
Andrew J. Steelman,
Jianrong Li
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2117636119
Subject(s) - experimental autoimmune encephalomyelitis , inflammasome , microglia , proinflammatory cytokine , caspase 1 , immunology , inflammation , autoimmunity , caspase , t cell , programmed cell death , biology , microbiology and biotechnology , apoptosis , immune system , biochemistry