
Blocking CHOP-dependent TXNIP shuttling to mitochondria attenuates albuminuria and mitigates kidney injury in nephrotic syndrome
Author(s) -
Sun-Ji Park,
Yeawon Kim,
Chuang Li,
Junwoo Suh,
Jothilingam Sivapackiam,
Tassia M. Goncalves,
George Jarad,
Guoyan Zhao,
Fumihiko Urano,
Vijay Sharma,
Ying Maggie Chen
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2116505119
Subject(s) - txnip , mitochondrion , inflammasome , albuminuria , cancer research , podocyte , biology , microbiology and biotechnology , chemistry , endocrinology , oxidative stress , thioredoxin , kidney , receptor , biochemistry , proteinuria