Open AccessDirect observation of reversible liquid–liquid transition in a trehalose aqueous solution
Author(s) -
Yoshiharu Suzuki
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2113411119
Subject(s) - aqueous solution , polyamorphism , chemistry , glass transition , isothermal process , melting point , crystallization , liquid liquid , analytical chemistry (journal) , thermodynamics , chromatography , organic chemistry , physics , polymer
Significance Recent studies on liquid water suggest that the two liquid waters exist in the supercooled temperature region and that their existence relates to the anomalous behavior of low-temperature liquid water such as the maximum density at 4 °C. However, the experimental investigation of two liquid waters is difficult because of the rapid crystallization. In this study, a reversible liquid–liquid transition in a trehalose aqueous solution by the change in pressure was observed directly. This result suggests strongly that two liquid waters exist in the aqueous solution. This study has implications for wide fields related to liquid water, such as solution chemistry, cryobiology, meteorology, and food engineering.