Open AccessTryptophan metabolism and bacterial commensals prevent fungal dysbiosis in Arabidopsis roots
Author(s) -
Katarzyna W. Wolinska,
Nathan Vannier,
Thorsten Thiergart,
Brigitte Pickel,
Sjoerd Gremmen,
Anna Piasecka,
Mariola PiślewskaBednarek,
Ryohei Thomas Nakano,
Youssef Belkhadir,
Paweł Bednarek,
Stéphane Hacquard
Publication year - 2021
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2111521118
Subject(s) - biology , commensalism , arabidopsis thaliana , dysbiosis , microbiology and biotechnology , mutant , bacteria , symbiosis , microbiome , botany , genetics , gene
Significance Understanding how host–microbe homeostasis is controlled and maintained in plant roots is key to enhance plant productivity. However, the factors that contribute to the maintenance of this equilibrium between plant roots and their multikingdom microbial communities remain largely unknown. Here, we observed a link between fungal load in roots and plant health, and we showed that modulation of fungal abundance is tightly controlled by a two-layer regulatory circuit involving the host innate immune system on one hand and bacterial root commensals on another hand. Our results shed a light into how host–microbe and microbe–microbe interactions act in concert to prevent dysbiosis inArabidopsis thaliana roots, thereby promoting plant health and maintaining growth-promoting activities of multikingdom microbial commensals.