SARS-CoV-2 prefusion spike protein stabilized by six rather than two prolines is more potent for inducing antibodies that neutralize viral variants of concern
Author(s) -
Mijia Lu,
Michelle Chamblee,
Yuexiu Zhang,
Chengjin Ye,
Piyush Dravid,
JunGyu Park,
KC Mahesh,
Sheetal Trivedi,
Satyapramod Murthy,
Himanshu Sharma,
Cole Cassady,
Supranee Chaiwatpongsakorn,
Xueya Liang,
Jacob S. Yount,
Prosper N. Boyaka,
Mark E. Peeples,
Luis MartínezSobrido,
Amit Kapoor,
Jiànróng Lǐ
Publication year - 2022
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2110105119
Subject(s) - immunogenicity , antibody , recombinant dna , biology , virology , microbiology and biotechnology , chemistry , immunology , biochemistry , gene
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