Open AccessSARS-CoV-2 prefusion spike protein stabilized by six rather than two prolines is more potent for inducing antibodies that neutralize viral variants of concern
Author(s) -
Mijia Lu,
Michelle Chamblee,
Yuexiu Zhang,
Chengjin Ye,
Piyush Dravid,
Jun-Gyu Park,
Mahesh Kc,
Sheetal Trivedi,
Satyapramod Murthy,
Himanshu Sharma,
Cole Cassady,
Supranee Chaiwatpongsakorn,
Xiaonan Liang,
Jacob S. Yount,
Prosper N. Boyaka,
Mark E. Peeples,
Luis Martínez-Sobrido,
Amit Kapoor,
Jiànróng Lǐ
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2110105119
Subject(s) - immunogenicity , antibody , biology , virology , recombinant dna , neutralizing antibody , microbiology and biotechnology , immunology , biochemistry , gene