Open AccessOrigin and early evolution of the plant terpene synthase family
Author(s) -
Qidong Jia,
Reid Brown,
Tobias G. Köllner,
Jianyu Fu,
Xinlu Chen,
Gane KaShu Wong,
Jonathan Gershenzon,
Reuben J. Peters,
Feng Chen
Publication year - 2022
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2100361119
Subject(s) - biology , plant evolution , gene , genome , secondary metabolism , gene duplication , terpene , terpenoid , atp synthase , biosynthesis , gene family , evolutionary biology , botany , genetics , biochemistry
Significance Land plants produce numerous terpenoids that regulate development and mediate environmental interactions. Thus, how typical plant terpene synthase (TPS ) genes originated and evolved to create terpenoid diversity is of fundamental interest. By investigatingTPSs from the genomes and transcriptomes of diverse taxa of green plants, it was demonstrated here that the ancestralTPS gene originated in land plants after divergence from green algae and encoded a bifunctionalent -kaurene synthase for phytohormone biosynthesis. This ancestralTPS then underwent gene duplication at least twice early in land plant evolution, leading to three ancientTPS lineages reflecting sub-functionalization of class I and II activities for phytohormone biosynthesis and neo-functionalization from primary to secondary metabolism, followed in each case by dynamic functional divergence.