Open AccessAdaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition
Author(s) -
Cuiqing Fan,
Chuntao Zhao,
Feng Zhang,
Meenu Kesarwani,
Zhaowei Tu,
Xiongwei Cai,
Ashley Kuenzi Davis,
Lingli Xu,
Cindy L. Hochstetler,
Xiaoyi Chen,
Fukun Guo,
Gang Huang,
Mohammad Azam,
Weidong Tian,
Q. Richard Lu,
Yi Zheng
Publication year - 2020
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2020102118
Subject(s) - pi3k/akt/mtor pathway , haematopoiesis , stem cell , mechanism (biology) , microbiology and biotechnology , rptor , biology , cancer research , gene , chemistry , signal transduction , genetics , philosophy , epistemology
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom