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Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody
Author(s) -
Bharat Madan,
Baoshan Zhang,
Kai Xu,
Cara W. Chao,
Sijy O’Dell,
Jacy R. Wolfe,
GwoYu Chuang,
Ahmed S. Fahad,
Hui Geng,
Rui Kong,
Mark K. Louder,
Thuy Duong Nguyen,
Reda Rawi,
Arne Schön,
Zizhang Sheng,
Rajani Nimrania,
Yiran Wang,
Tongqing Zhou,
Bob C. Lin,
Nicole A. DoriaRose,
Lawrence Shapiro,
Peter D. Kwong,
Brandon J. DeKosky
Publication year - 2021
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2011653118
Subject(s) - neutralizing antibody , virology , antibody , biology , hiv vaccine , human immunodeficiency virus (hiv) , genetics , computational biology , vaccine trial

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