Open AccessHow adding a single methylene to dihydrofolate reductase can change its conformational dynamics
Author(s) -
Ryan W. Penhallurick,
A Scheraga Harold,
Maya D. Durnal,
Toshiko Ichiye
Publication year - 2021
Publication title -
the journal of chemical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.071
H-Index - 357
eISSN - 1089-7690
pISSN - 0021-9606
DOI - 10.1063/5.0047942
Subject(s) - dihydrofolate reductase , molecular dynamics , glutamic acid , aspartic acid , chemistry , active site , biophysics , protein dynamics , side chain , amino acid , residue (chemistry) , protein structure , methylene , biochemistry , enzyme , stereochemistry , biology , computational chemistry , organic chemistry , polymer
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom