SOS1 interacts with Grb2 through regions that induce closed nSH3 conformations
Author(s) -
Tsung-Jen Liao,
Hyunbum Jang,
David Fushman,
Ruth Nussinov
Publication year - 2020
Publication title -
the journal of chemical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.071
H-Index - 357
eISSN - 1089-7690
pISSN - 0021-9606
DOI - 10.1063/5.0013926
Subject(s) - guanine nucleotide exchange factor , grb2 , signal transducing adaptor protein , sh3 domain , chemistry , binding site , sh2 domain , peptide , plasma protein binding , gtp' , stereochemistry , molecular dynamics , biophysics , proto oncogene tyrosine protein kinase src , microbiology and biotechnology , biology , biochemistry , signal transduction , computational chemistry , enzyme
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