Modification of microneedles using inkjet printing | Zendy

Ryan D. Boehm | Zendy; Philip Miller | Zendy; S.L. Hayes | Zendy; Nancy A. MonteiroRiviere | Zendy; Roger J. Narayan | Zendy

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Modification of microneedles using inkjet printing

Author(s) -

Ryan D. Boehm,

Philip Miller,

S.L. Hayes,

Nancy A. MonteiroRiviere,

Roger J. Narayan

Publication year - 2011

Publication title -

aip advances

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.421

H-Index - 58

ISSN - 2158-3226

DOI - 10.1063/1.3602461

Subject(s) - stereolithography , materials science , fabrication , nanotechnology , nanoindentation , copolymer , composite material , polymer , medicine , alternative medicine , pathology

In this study, biodegradable acid anhydride copolymer microneedles containing quantum dots were fabricated by means of visible light dynamic mask micro-stereolithography-micromolding and inkjet printing. Nanoindentation was performed to obtain the hardness and the Young's modulus of the biodegradable acid anhydride copolymer. Imaging of quantum dots within porcine skin was accomplished by means of multiphoton microscopy. Our results suggest that the combination of visible light dynamic mask micro-stereolithography-micromolding and inkjet printing enables fabrication of solid biodegradable microneedles with a wide range of geometries as well as a wide range of pharmacologic agent compositions

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